Thanks for the response. Yes, Risperdal antagonizes receptors for dopamine, yet this hasn’t stopped it being used for ADHD. I couldn’t say how widely spread such use is, but it certainly does exist, and all the time I hear or read about it when researching medication treatments for that condition. I too would love to hear more about how doctor’s are rewarded for their prescribing habits.

Best wishes,
David

Just a quick note to expand on what you’ve written – it doesn’t seem likely (though perhaps not impossible) that risperidone would be routinely prescribed for ADHD, given its status as a D3 receptor antagonist (among other things). Most first line drug treatments for ADHD are NDRI’s (norepinephrine and dopamine reuptake inhibitors) like methylphenidate or dextroamphetamine, which you’ve covered already in this blog. Risperidone only has FDA approval for the big three – schizophrenia, bipolar disorder and autism, but of course the off label uses run rampant. I do wonder exactly what kind of compensation is involved to the prescribing doctors?