What is colesterol or cholesterol?

Monday, November 30th, 2009
Counting Cholesterol

What is colesterol or cholesterol?

Colesterol (Spanish for cholesterol) is a steroid that plays an important function in the body. It is used in many different cells to make important structures. That said, cholesterol also plays a major role in heart disease.

From a general perspective, there are two main types of cholesterol: low density lipoprotein, LDL, high density lipoprotein, or HDL. The general rule is that LDL is “bad,” and HDL is “good,” though what that means isn’t exactly clear.

Heart disease can occur when cholesterol builds up on arteries and helps in the formation of a plaque. This can be fatal because the plaques can clog the blood vessels completely. Imagine a lead pipe with a big pile of goo in the middle – water wouldn’t be able to go through it.

That’s what happens in your body pretty much, with cholesterol and your body’s own form of goo.

Additionally, the plaques can break off and float around, which doesn’t sound too bad. That is, until they reach a small enough blood vessel that they can block entirely, causing anything ranging from a stroke, deep venous thrombosis, or heart attack.

Colesterol or cholesterol is reused by the body, and you get a lot of it from your diet.

Some major medications lower cholesterol levels such as the statins.

What are healthy cholesterol levels?

As per the American Heart Association, total cholesterol levels should be lower than 200 mg/dl.

LDL levels should be optimally below 100 mg/dl

100 to 130 mg/dl is not too high risk of disease

130 to 160 mg/dl is moderately elevated

160 mg/dl and up is at significant risk of disease

HDL levels should be optimally be above 60 mg/dl

Less than 50 mg/dl of HDL is high risk for women

Less than 40 mg/dl of HDL is high risk for men

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What is Sleep Apnea?

Monday, July 13th, 2009

Do you snore, wake up often at night, and feel excessively drowsy during the day?

You might have sleep apnea, a sleeping disorder that plays a role in hypertension, diabetes and mental illness.

What is sleep apnea?

Sleep apnea is very common.  2-4% of people in North America suffer from some form.

To test if you have it, take the Epworth sleepiness scale.  A high score indicates some sort of sleeping problem.

Sleep apnea, logically enough, means that you suffer apnea during your sleep.  Apnea is defined as a cessation of breathing for more than 10 seconds.

Full blown sleep apnea means that you stop breathing many times per hour, which disrupts the quality of your sleep.  Hypoapnea is a milder form, defined as “only” a 50% reduction in airflow.

Obstructive sleep apnea (OSA) is the most common form and is caused by the airway around the mouth becoming blocked because of various physical changes associated with sleep.

Central sleep apnea, the less common form, is caused by your body not sending the right signals to the lungs.

Both forms stop your breathing.  Cut off from oxygen, the body briefly wakes up to restore proper breathing, which interrupts sleep.  The problems this causes are serious.

CPAP is the standard of care

Continous positive airway pressure machines are the most effective treatment for sleep apnea.  That said, they’re bulky and half of patients stop using them within a year.  But they provide significant increase in breathing and help treat the symptoms caused by the apnea.

What are Oral Appliances?

Oral appliances (OA) are very similar to mouth guards.  You put them in your mouth, and they hopefully help you with breathing during the night.

Patients say OA are more convenient than CPAP, but at the same time provide less symptom relief.  The medical data shows that indeed, OA do provide some relief but CPAP is superior at restoring normal function.

What are surgical options?

See here.

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Link to Mental Disorders:

OSA is highly associated with mental disorders.  One study of OSA patients found that 21% had depression, 16.7% anxiety disorders, and 11.9% PTSD.

Treatment of the psychological issues can, interestingly enough, sometimes reduce the OSA, but the data on this is limited.

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